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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR3
All Species:
15.15
Human Site:
T410
Identified Species:
30.3
UniProt:
P22607
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22607
NP_000133.1
806
87710
T410
K
K
G
L
G
S
P
T
V
H
K
I
S
R
F
Chimpanzee
Pan troglodytes
XP_521622
819
91776
K417
S
S
Q
P
A
V
H
K
L
T
K
R
I
P
L
Rhesus Macaque
Macaca mulatta
XP_001101108
806
87642
T410
K
K
G
L
G
S
P
T
V
H
K
I
S
R
F
Dog
Lupus familis
XP_545926
833
90729
T437
K
K
G
L
G
S
P
T
V
H
K
V
S
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q61851
801
87739
T404
K
K
G
L
G
S
P
T
V
H
K
V
S
R
F
Rat
Rattus norvegicus
Q04589
822
91806
K416
H
S
Q
M
A
V
H
K
L
A
K
S
I
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
V404
K
A
M
N
T
T
T
V
Q
K
V
S
K
F
P
Frog
Xenopus laevis
O42127
802
89497
V400
K
S
M
T
A
P
P
V
H
K
V
S
K
F
P
Zebra Danio
Brachydanio rerio
Q9I8X3
800
89698
P398
Q
K
T
L
P
A
P
P
V
Q
K
L
S
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
S368
P
E
G
G
G
D
S
S
G
S
M
D
T
M
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
P578
R
V
V
V
S
K
R
P
M
N
E
D
N
E
N
Sea Urchin
Strong. purpuratus
Q26614
972
110463
H577
C
K
Q
T
Q
V
R
H
R
R
P
S
D
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.1
89.3
N.A.
92.4
62.9
N.A.
N.A.
80.1
70.5
73.8
N.A.
37.5
N.A.
31.3
35.4
Protein Similarity:
100
77.5
99.2
91.9
N.A.
94.7
76.2
N.A.
N.A.
87.5
79.4
82.3
N.A.
54
N.A.
46.6
50
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
6.6
N.A.
N.A.
6.6
13.3
46.6
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
20
N.A.
N.A.
13.3
13.3
73.3
N.A.
33.3
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
25
9
0
0
0
9
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
17
9
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
9
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
42
% F
% Gly:
0
0
42
9
42
0
0
0
9
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
17
9
9
34
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
17
17
0
9
% I
% Lys:
50
50
0
0
0
9
0
17
0
17
59
0
17
17
0
% K
% Leu:
0
0
0
42
0
0
0
0
17
0
0
9
0
0
17
% L
% Met:
0
0
17
9
0
0
0
0
9
0
9
0
0
9
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
9
0
0
9
0
9
% N
% Pro:
9
0
0
9
9
9
50
17
0
0
9
0
0
17
25
% P
% Gln:
9
0
25
0
9
0
0
0
9
9
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
17
0
9
9
0
9
0
34
0
% R
% Ser:
9
25
0
0
9
34
9
9
0
9
0
34
42
0
0
% S
% Thr:
0
0
9
17
9
9
9
34
0
9
0
0
9
0
0
% T
% Val:
0
9
9
9
0
25
0
17
42
0
17
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _